Copper-Catalyzed Cross-Dehydrogenative Coupling (CDC) of Alkynes and Benzylic C-H Bonds

被引：94

作者：

Correia, Camille A. ^{[1
]}

Li, Chao-Jun ^{[1
]}

机构：

[1] McGill Univ, Dept Chem, Montreal, PQ H3A 2K6, Canada

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 09期

基金：

加拿大自然科学与工程研究理事会;

关键词：

alkynes; C-C coupling; C-H activation; copper; diphenylmethanes; OXIDATIVE ACTIVATION; HYDROXYL-GROUPS; FUNCTIONALIZATION; ALKYNYLATION; ALKYLATION; ETHERS; ARENES; SUBSTITUTION; CHEMISTRY; ADJACENT;

D O I：

10.1002/adsc.201000066

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The activation of benzylic C-H bonds and subsequent coupling with terminal alkynes in the presence of 2,3-dichloro-5,6-dicyanoquinone (DDQ) and a catalytic amount of copper(I) triflate is presented. Good to moderate yields of disubstituted alkynes are obtained for this cross-dehydrogenative coupling (CDC) reaction between a variety of aromatic alkynes and diphenylmethane derivatives.

引用

页码：1446 / 1450

页数：5

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