MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems

被引：314

作者：

Herranz, Hector ^{[1
]}

Cohen, Stephen M. ^{[1
,2
]}

机构：

[1] Inst Mol & Cell Biol, Singapore 138673, Singapore

[2] Natl Univ Singapore, Dept Biol Sci, Singapore 117604, Singapore

来源：

GENES & DEVELOPMENT | 2010年 / 24卷 / 13期

关键词：

MicroRNAs; noise; robustness; regulatory networks; MIR-200; FAMILY; FEEDBACK; MOTIFS; ROBUSTNESS; EXPRESSION; SENSELESS; MODULATE; ELEGANS; CELLS; LOOPS;

D O I：

10.1101/gad.1937010

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Biological systems are continuously challenged by an environment that is variable. Yet, a key feature of developmental and physiological processes is their remarkable stability. This review considers how microRNAs contribute to gene regulatory networks that confer robustness.

引用

收藏

页码：1339 / 1344

页数：6

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