Polyacetylenes from Bupleurum longiradiatum

被引：26

作者：

Huang, Hai-Qiang ^{[1
]}

Zhang, Xi ^{[1
]}

Shen, Yun-Heng ^{[1
]}

Su, Juan ^{[1
]}

Liu, Xiao-Hua ^{[1
]}

Tian, Jun-Min ^{[1
]}

Lin, Sheng ^{[1
]}

Shan, Lei ^{[1
]}

Zhang, Wei-Dong ^{[1
,2
]}

机构：

[1] Second Mil Med Univ, Sch Pharm, Dept Nat Med Chem, Shanghai 200433, Peoples R China

[2] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 12期

关键词：

SAIKOSAPONINS; TERPENOIDS;

D O I：

10.1021/np900534v

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Eight new polyacetylenes (1-8) and six known polyacetylenes were isolated from the entire parts of Bupleurum longiradiatum, a poisonous plant. The structures of the new compounds were determined by spectroscopic data interpretation. The absolute configuration of the known Compound bupleurotoxin (9) was established by the modified Mosher's method. All isolates were also tested for their cytotoxicity against a human leukemia cell line (HL-60).

引用

页码：2153 / 2157

页数：5

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