Re-structuring the host cell:: up close with Salmonella's molecular machinery

被引：10

作者：

Lilic, A ^{[1
]}

Stebbins, CE ^{[1
]}

机构：

[1] Rockefeller Univ, Lab Struct Microbiol, New York, NY 10021 USA

来源：

MICROBES AND INFECTION | 2004年 / 6卷 / 13期

关键词：

Salmonella; Type III secretion; actin; Rho GTP-binding proteins; X-ray crystallography;

D O I：

10.1016/j.micinf.2004.08.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A common theme in bacterial disease is the manipulation of the eukaryotic cytoskeleton by pathogenic factors. Understanding how virulence factors operate to achieve these alterations is a growing and important research effort. This review focuses on several virulence factors from the pathogen Salmonella, and considers the contributions of structural biology to our appreciation of bacterial modulation of cytoskeletal dynamics. (C) 2004 Elsevier SAS. All rights reserved.

引用

页码：1205 / 1211

页数：7

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