Electron transfer rates in DNA films as a function of tether length

被引：95

作者：

Drummond, TG

Hill, MG ^{[1
]}

Barton, JK

机构：

[1] CALTECH, Dept Chem & Chem Engn, Pasadena, CA 91125 USA

[2] Occidental Coll, Dept Chem, Los Angeles, CA 90041 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 46期

关键词：

D O I：

10.1021/ja044910i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A homologous series of DNA-modified electrodes has been investigated in which the molecular tether length varies. Using intercalated, covalently bound daunomycin as a redox probe, an exponential dependence of electron transfer rates on the number of intervening methylene groups in the σ-bonded tether is observed. In contrast, variation in DM position within DNA yields no detectable change in rate. These data confirm that overall electron transfer rates in DNA films are limited by the tether, not the DNA. Copyright © 2004 American Chemical Society.

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页码：15010 / 15011

页数：2

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