Rover: A tool to visualize and validate quantitative proteomics data from different sources

被引：34

作者：

Colaert, Niklaas ^{[1
,2
]}

Helsens, Kenny ^{[2
]}

Impens, Francis ^{[1
,2
]}

Vandekerckhove, Joel ^{[1
,2
]}

Gevaert, Kris ^{[1
,2
]}

机构：

[1] VIB, Dept Med Prot Res, Ghent, Belgium

[2] Univ Ghent, Dept Biochem, B-9000 Ghent, Belgium

来源：

PROTEOMICS | 2010年 / 10卷 / 06期

关键词：

Bioinformatics; Manual validation; MASCOT Distiller; MaxQuant; Protein inference; Quantitative proteomics; PROTEIN; IDENTIFICATION;

D O I：

10.1002/pmic.200900379

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Manual validation of regulated proteins found in MS-driven quantitative proteome studies is tedious. Here we present Rover (http://genesis.ugent.be/rover), a tool that facilitates this process. Rover accepts quantitative data from different sources such as MASCOT Distiller and MaxQuant and, in an intuitive environment, Rover visualizes these data such that the user can select and validate algorithm-suggested regulated proteins in the frame of the whole experiment and in the context of the protein inference problem.

引用

页码：1226 / 1229

页数：4

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