A review on chitosan centred scaffolds and their applications in tissue engineering

被引：199

作者：

Ahmed, Shakeel ^{[1
]}

Annu ^{[2
]}

Ali, Akbar ^{[3
]}

Sheikh, Javed ^{[4
]}

机构：

[1] Govt Degree Coll Mendhar, Dept Chem, Mendhar 185211, Jammu & Kashmir, India

[2] Jamia Millia Islamia, Dept Chem, Bio Polymers Res Lab, New Delhi 110025, India

[3] Jamia Millia Islamia, Dept Chem, New Delhi 110025, India

[4] Indian Inst Technol Delhi, Dept Text Technol, New Delhi 110016, India

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2018年 / 116卷

关键词：

Biomaterials; Chitosan; Scaffolds; Tissue engineering; SYNTHETIC EXTRACELLULAR-MATRIX; PHOSPHATE COMPOSITE SCAFFOLDS; PEG-GRAFTED CHITOSAN; NANOFIBROUS SCAFFOLDS; GRAPHENE OXIDE; 3-DIMENSIONAL SCAFFOLDS; NANOCOMPOSITE SCAFFOLDS; GALACTOSYLATED CHITOSAN; MECHANICAL-PROPERTIES; CHITIN NANOCRYSTALS;

D O I：

10.1016/j.ijbiomac.2018.04.176

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The diversity and availability of biopolymer and increased clinical demand for safe scaffolds lead to an increased interest in fabricating scaffolds in order to achieve fruitful progress in tissue engineering. Chitosan is a biopolymer obtained by de-acetylation of chitin extracted from shells of crustaceans and fungi. Due to the presence of reactive functionality in the molecular chain chitosan can be modified either chemically or physically to fabricate the tailor-made scaffolds having desired properties for tissue engineering centred applications. In this review chitosan, its properties and role either virgin, chemically or physically modified, 2D or 3D scaffolds for tissue engineering application have been highlighted. (C) 2018 Elsevier B.V. All rights reserved.

引用

页码：849 / 862

页数：14

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