Organo cerium reagents in organic chemistry: General method of synthesis of alkyl substituted 1,3-diols by RLi-CeCl3 addition to beta-hydroxyketones.

被引：11

作者：

Bartoli, G ^{[1
]}

Bosco, M ^{[1
]}

VanBeek, J ^{[1
]}

Sambri, L ^{[1
]}

Marcantoni, E ^{[1
]}

机构：

[1] UNIV CAMERINO, DIPARTIMENTO SCI CHIM, I-62032 CAMERINO, MC, ITALY

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 13期

关键词：

D O I：

10.1016/0040-4039(96)00246-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Organocerium compounds (RLi-CeCl3) are able to transfer an alkyl group to the carbonylic function of a beta-hydroxyketone giving alkyl substituted 1,3-diols in excellent yields. The use of these not sophisticated reagents is essential to depress undesired dimetallation and retroaldol side processes.

引用

页码：2293 / 2296

页数：4

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