Production of clavulanic acid and cephamycin C by Streptomyces clavuligerus in palm-oil medium

被引：22

作者：

Lee, PC ^{[1
]}

Ho, CC ^{[1
]}

机构：

[1] UNIV MALAYA,DEPT BIOL CELLULAR & GENET,KUALA LUMPUR 59100,MALAYSIA

来源：

WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY | 1996年 / 12卷 / 01期

关键词：

cephamycin C; clavulanic acid; lipid; mutation; Streptomyces clavuligerus;

D O I：

10.1007/BF00327805

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Palm and palm-kernel oils and their olein and stearin fractions were suitable as the main carbon sources for growth and production of clavulanic acid by Streptomyces clavuligerus. However, oleic and lauric acids were not utilized for growth. A spontaneous mutant, which was selected for higher cephamycin C production, also produced more clavulanic acid with these oils in the medium.

引用

页码：73 / 75

页数：3

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