Bis-zirconium and bis-hafnium catalysts for the strong activation of carbonyl substrates

被引：45

作者：

Hanawa, H

Kii, S

Asao, N

Maruoka, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Kyoto 6068502, Japan

[2] Hokkaido Univ, Grad Sch Sci, Dept Chem, Sapporo, Hokkaido 0600810, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 29期

关键词：

allylation; aldol reactions; asymmetric reactions; zirconium and compounds;

D O I：

10.1016/S0040-4039(00)00827-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(3,3'-Di-t-butyl-5,5'-dimethylbenzophenone-2,2'-dioxy)bis(triisopropoxyzirconium) and its hafnium derivative can be successfully utilized in organic synthesis as bimetallic Lewis acid catalysts. The high activation ability of such catalysts toward carbonyls is emphasized using several synthetic examples including the asymmetric allylation in comparison with the corresponding mono-Zr as well as bis-Ti catalysts. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：5543 / 5546

页数：4

共 46 条

[41] CATALYTIC AND STOICHIOMETRIC ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES USING A NOVEL CHIRAL SPIROTITANATE [J].