Assembly: a resource for assembled genomes at NCBI

被引：239

作者：

Kitts, Paul A. ^{[1
]}

Church, Deanna M. ^{[1
,2
]}

Thibaud-Nissen, Francoise ^{[1
]}

Choi, Jinna ^{[1
]}

Hem, Vichet ^{[1
]}

Sapojnikov, Victor ^{[1
]}

Smith, Robert G. ^{[1
]}

Tatusova, Tatiana ^{[1
]}

Xiang, Charlie ^{[1
]}

Zherikov, Andrey ^{[1
]}

DiCuccio, Michael ^{[1
]}

Murphy, Terence D. ^{[1
]}

Pruitt, Kim D. ^{[1
]}

Kimchi, Avi ^{[1
]}

机构：

[1] NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20894 USA

[2] Personalis Inc, Menlo Pk, CA 94025 USA

来源：

NUCLEIC ACIDS RESEARCH | 2016年 / 44卷 / D1期

基金：

美国国家卫生研究院;

关键词：

READ ALIGNMENT; DRAFT GENOME; METABOLISM; SEQUENCE; METADATA; DATABASE;

D O I：

10.1093/nar/gkv1226

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The NCBI Assembly database (www.ncbi.nlm.nih.gov/assembly/) provides stable accessioning and data tracking for genome assembly data. The model underlying the database can accommodate a range of assembly structures, including sets of unordered contig or scaffold sequences, bacterial genomes consisting of a single complete chromosome, or complex structures such as a human genome with modeled allelic variation. The database provides an assembly accession and version to unambiguously identify the set of sequences that make up a particular version of an assembly, and tracks changes to updated genome assemblies. The Assembly database reports metadata such as assembly names, simple statistical reports of the assembly (number of contigs and scaffolds, contiguity metrics such as contig N50, total sequence length and total gap length) as well as the assembly update history. The Assembly database also tracks the relationship between an assembly submitted to the International Nucleotide Sequence Database Consortium (INSDC) and the assembly represented in the NCBI RefSeq project. Users can find assemblies of interest by querying the Assembly Resource directly or by browsing available assemblies for a particular organism. Links in the Assembly Resource allow users to easily download sequence and annotations for current versions of genome assemblies from the NCBI genomes FTP site.

引用

页码：D73 / D80

页数：8

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