Electrokinetic flow control for composition modulation in a microchannel

被引：45

作者：

Tang, ZL ^{[1
]}

Hong, SB

Djukic, D

Modi, V

West, AC

Yardley, J

Osgood, RM

机构：

[1] Columbia Univ, Dept Chem Engn, New York, NY 10027 USA

[2] Columbia Univ, Dept Mech Engn, New York, NY 10027 USA

[3] Columbia Univ, Dept Elect Engn, New York, NY 10027 USA

来源：

JOURNAL OF MICROMECHANICS AND MICROENGINEERING | 2002年 / 12卷 / 06期

关键词：

D O I：

10.1088/0960-1317/12/6/319

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A numerical and experimental study of the injection into a microchannel of a fluid with a spatially modulated composition is presented. The investigation employs test structures constructed in polydimethylsiloxane by standard replica molding. Fluid-flow simulations are compared to flow results obtained by fluorescence microscopy experiments. Results show that for a given channel dimension, the desired modulation of the solution composition is only possible below a threshold frequency. The value of the threshold frequency is dependent on channel size as well as flow rate. Experimental results are in accord with numerical simulations and theoretical considerations.

引用

页码：870 / 877

页数：8

共 22 条

[1] Serum modulates the intracellular calcium response of primary cultured bone cells to shear flow [J].

Allen, FD ;

Hung, CT ;

Pollack, SR ;

Brighton, CT .

JOURNAL OF BIOMECHANICS, 2000, 33 (12) :1585-1591

[2]

ARNOLD DW, 1999, SPIE C MICR DEV 2 SA, P174

[3]

BRAHMASANDRA SN, 1998, SPIE C MICR DEV SANT, P242

[4] Irrotationality of uniform electroosmosis [J].

Cummings, EB ;

Griffiths, SK ;

Nilson, RH .

MICROFLUIDIC DEVICES AND SYSTEMS II, 1999, 3877 :180-189

[5]

deBeer D, 1997, BIOTECHNOL BIOENG, V53, P151, DOI 10.1002/(SICI)1097-0290(19970120)53:2<151::AID-BIT4>3.0.CO

[6]

2-N

[7]

DESHPANDE M, 2000, SOL STAT SENS ACT WO, P128

[8] High-aspect-ratio, ultrathick, negative-tone near-UV photoresist for MEMS applications [J].

Despont, M ;

Lorenz, H ;

Fahrni, N ;

Brugger, J ;

Renaud, P ;

Vettiger, P .

MEMS 97, PROCEEDINGS - IEEE THE TENTH ANNUAL INTERNATIONAL WORKSHOP ON MICRO ELECTRO MECHANICAL SYSTEMS: AN INVESTIGATION OF MICRO STRUCTURES, SENSORS, ACTUATORS, MACHINES AND ROBOTS, 1997, :518-522

[9] GLASS CHIPS FOR HIGH-SPEED CAPILLARY ELECTROPHORESIS SEPARATIONS WITH SUBMICROMETER PLATE HEIGHTS [J].

EFFENHAUSER, CS ;

MANZ, A ;

WIDMER, HM .

ANALYTICAL CHEMISTRY, 1993, 65 (19) :2637-2642

[10] Computer simulations of electrokinetic injection techniques in microfluidic devices [J].

Ermakov, SV ;

Jacobson, SC ;

Ramsey, JM .

ANALYTICAL CHEMISTRY, 2000, 72 (15) :3512-3517

← 1 2 3 →