A straightforward preparation of amino-polystyrene resin from Merrifield resin

被引：33

作者：

Arseniyadis, S ^{[1
]}

Wagner, A ^{[1
]}

Mioskowski, C ^{[1
]}

机构：

[1] Univ Strasbourg 1, UMR 7514, CNRS, Lab Synth Bioorgan,Fac Pharm, F-67401 Illkirch Graffenstaden, France

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 52期

关键词：

solid phase synthesis; amino-polystyrene; Schmidt rearrangement; triazene linker;

D O I：

10.1016/S0040-4039(02)02192-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Azidomethyl-polystyrene, obtained by nucleophilic substitution of chloromethyl-polystyrene, undergoes a Schmidt rearrangement when treated with trifluoromethanesulfonic acid, affording amino-polystyrene. To assess its loading and reactivity the resin is used as a support for the preparation of triazene-linked amine. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：9717 / 9719

页数：3

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