Dietary exposure of Canadians to perfluorinated carboxylates and perfluorooctane sulfonate via consumption of meat, fish, fast foods, and food items prepared in their packaging

被引:356
作者
Tittlemier, Sheryl A. [1 ]
Pepper, Karen
Seymour, Carol
Moisey, John
Bronson, Roni
Cao, Xu-Liang
Dabeka, Robert W.
机构
[1] Hlth Canada, Food Res Div, Banting Res Ctr 2203D, Ottawa, ON K1A 0L2, Canada
[2] Hlth Canada, Chem Hlth Hazard Assessment Div, Banting Res Ctr 2204D, Ottawa, ON K1A 0L2, Canada
关键词
PFOS; PFOA; diet; food; exposure estimate;
D O I
10.1021/jf0634045
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
Human exposure to perfluorinated compounds is a worldwide phenomenon; however, routes of human exposure to these compounds have not been well-characterized. Fifty-four solid food composite samples collected as part of the Canadian Total Diet Study (TDS) were analyzed for perfluorocarboxylates and perfluorooctanesulfonate (PFOS) using a methanol extraction liquid chromatography tandem mass spectrometry method. Foods analyzed included fish and seafood, meat, poultry, frozen entrees, fast food, and microwave popcorn collected from 1992 to 2004 and prepared as for consumption. Nine composites contained detectable levels of perfluorinated compoundsfour meat-containing, three fish and shellfish, one fast food, and one microwave popcorn. PFOS and perfluorooctanoate (PFOA) were detected the most frequently; concentrations ranged from 0.5 to 4.5 ng/g. The average dietary intake of total perfluorocarboxylates and PFOS for Canadians was estimated to be 250 ng/day, using results from the 2004 TDS composites. A comparison with intakes of perfluorocarboxylates and PFOS via other routes (air, water, dust, treated carpeting, and apparel) suggested that diet is an important source of these compounds. There was a substantial margin of exposure between the toxicological points of reference and the magnitude of dietary intake of perfluorinated compounds for Canadians >= 12 years old.
引用
收藏
页码:3203 / 3210
页数:8
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