Imaging of RNA delivery to cells by thiazole orange as a fluorescent RNA base substitution

被引:15
作者
Berndl, Sina [2 ]
Breunig, Miriam [1 ]
Goepferich, Achim [1 ]
Wagenknecht, Hans-Achim [1 ]
机构
[1] Univ Regensburg, Inst Pharm, D-93040 Regensburg, Germany
[2] Univ Regensburg, Inst Organ Chem, D-93040 Regensburg, Germany
关键词
NUCLEIC-ACID; LIVING CELLS; MESSENGER-RNA; MOLECULAR BEACONS; FIT PROBES; DNA; HYBRIDIZATION; COMPLEXES; DESIGN;
D O I
10.1039/b921227b
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Interstrand thiazole orange (TO) dimers in RNA show a yellow colored emission that can be distinguished from the green TO monomer emission by confocal microscopy inside CHO cells.
引用
收藏
页码:997 / 999
页数:3
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