Distribution of TiO2 particles in the olfactory bulb of mice after nasal inhalation using microbeam SRXRF mapping techniques

被引：44

作者：

Wang, J. X. ^{[1
]}

Chen, C. Y.

Yu, H. W.

Sun, J.

Li, B.

Li, Y. F.

Gao, Y. X.

He, W.

Huang, Y. Y.

Chai, Z. F.

Zhao, Y. L.

Deng, X. Y.

Sun, H. F.

机构：

[1] Chinese Acad Sci, Key Lab Nucl Analyt Tech, Inst High Energy Phys, Beijing 100049, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

[3] Chinese Acad Sci, Synchrotron Radiat Facil Lab, Inst High Energy Phys, Beijing 100049, Peoples R China

[4] Shenzhen Univ, Inst Nucl Technol, Shenzhen 518060, Peoples R China

[5] Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | 2007年 / 272卷 / 03期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1007/s10967-007-0617-z

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The characterization of different sized TiO2 (25 nm, 80 nm, and 155 nm) was carried out by transmission electron microscopy (TEM) and the micro-distributions of TiO2 in the olfactory bulb of mice after nasal inhalation were investigated by microbeam SRXRF mapping techniques. The results show that TiO2 particles can be translocated to the olfactory bulb through the olfactory nerve system after inhalation. The distributions of Fe, Cu, and Zn in the olfactory bulb were also studied.

引用

页码：527 / 531

页数：5

共 18 条

[11] Manufactured nanomaterials (Fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass [J].