Variation in Antioxidant Activity and Phenolic and Flavonoid Contents in the Flowers and Leaves of Ghaneri (Lantana camara L.) as Affected by Different Extraction Solvents

被引:16
作者
Anwar, Farooq [1 ]
Shaheen, Nusrat [2 ]
Shabir, Ghulam [2 ,3 ]
Ashraf, Muhammad [4 ]
Alkharfy, Khalid M. [5 ]
Gilani, Anwarul-Hassan [6 ,7 ]
机构
[1] Univ Sargodha, Dept Chem, Sargodha 40100, Pakistan
[2] Univ Agr Faisalabad, Dept Chem & Biochem, Faisalabad 38040, Pakistan
[3] Natl Inst Biotechnol & Genet Engn, Environm Biotechnol Div, Faisalabad, Pakistan
[4] Univ Sargodha, Univ Coll Agr, Sargodha 40100, Pakistan
[5] King Saud Univ, Coll Pharm, Dept Pharm, Riyadh, Saudi Arabia
[6] Aga Khan Univ, Dept Biol & Biomed Sci, Karachi, Pakistan
[7] Mekelle Univ, Coll Hlth Sci, Dept Pharm, Mekelle, Ethiopia
关键词
Lantana camara; solvent extracts; phenolics compounds; antioxidant activities; radical scavengers; reducing power; MEDICINAL-PLANTS; ANTIMICROBIAL ATTRIBUTES; BARK; CAPACITY; FRUIT; VARIETIES; METHANOL; SEEDS;
D O I
10.3923/ijp.2013.442.453
中图分类号
R9 [药学];
学科分类号
100702 [药剂学];
摘要
The current study reports variation in antioxidant activity and phenolic and flavonoid contents in the flowers and leaves of a medicinal herb Ghaneri (Lantana camara L.) as affected by different extraction solvents (80% methanol, 80% ethanol, absolute methanol and absolute ethanol). The antioxidant activity was assessed by measuring the reducing power, inhibition in linoleic acid peroxidation and 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH center dot) scavenging activity. Of the extracts tested, flower extract produced by 80% methanol possessed maximum amount of total phenolics (21.4 g GAE/100 g DW), total flavonoids (13.8 g CE/100 g DW), reducing power (0.095 for extract concentration of 1.0 mg mL(-1)), inhibition of linoleic acid peroxidation (83.3%) and DPPH radical scavenging activity (72.3%). A significant difference was observed for phenolic and flavonoid contents and antioxidant activity in relation to different extraction solvents and plant parts analyzed (p<0.05) thus prompting the need for utilization of appropriate solvent media and material for isolation of maximum amount of antioxidants. The results of this study explore the potential of L. camara as a rich source of natural antioxidants for development of functional foods and nutraceutical applications.
引用
收藏
页码:442 / 453
页数:12
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