Neo-clerodane diterpenoids from Scutellaria galericulata

被引：19

作者：

Rodriguez, B

DelaTorre, MC

Rodriguez, B

GomezSerranillos, P

机构：

[1] CSIC,INST QUIM ORGAN GEN,E-28006 MADRID,SPAIN

[2] UNIV COMPLUTENSE MADRID,FAC FARM,DEPT FARMACOL,E-28040 MADRID,SPAIN

来源：

PHYTOCHEMISTRY | 1996年 / 41卷 / 01期

关键词：

Scutellaria galericulata; labiatae; neoclerodane diterpenes; scutegalins C and D;

D O I：

10.1016/0031-9422(95)00521-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new neo-clerodane diterpenoids, scutegalin C and D, have been isolated from the acetone extract of the aerial parts of Scutellaria galericulata. The structures of the new compounds were established by chemical and spectroscopic means as (13S, 19R)-6 alpha-acetoxy-4 alpha,18-epoxy-7 beta-tigloyloxy-neo-cleroda-(19-O-tigloyl)-19,2 alpha, 16,15-dihemiacetal (scutegalin C) and (13S,19R)-6 alpha-acetoxy-4 alpha,18-epoxy-neo-cleroda-(19-O-tigloyl)-19,2 alpha, 16,15-dihemiacetal (scutegalin D). The absolute stereochemistry of scutegallin C was determined by chemical correlation with the already known neo-clerodane scutegalin B.

引用

页码：247 / 253

页数：7