Arylcarbamoylated allylcarbamido-β-cyclodextrin:: synthesis and immobilization on nonfunctionalized silica gel as a chiral stationary phase

被引：16

作者：

Bai, ZW

Lai, XH

Chen, L

Ching, CB

Ng, SC ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

[2] Natl Univ Singapore, Chem & Proc Engn Ctr, Singapore 119260, Singapore

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 39期

关键词：

allylcarbamido-beta-cyclodextrin; arylcarbamate; hydrosilylation; silanization; chiral stationary phase; enantioseparation;

D O I：

10.1016/j.tetlet.2004.08.007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four new chiral stationary phases based on mono-(6(A)-allylcarbamido-6(A)-deoxy)-arylcarbamoylated beta-cyclodextrin were synthesized. The chiral stationary phase of phenylcarbamoylated beta-cyclodextrin exhibited excellent separation capability for a variety of chiral compounds. Compared with the previous work, it was found that the spacer remained on the surface of the silica gel and decreased the enantioseparation capability. (C) 2004 Elsevier Ltd. All rights reserved.

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收藏

页码：7323 / 7326

页数：4

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