Visualization of pathogenicity regions in bacteria

被引：8

作者：

Friis, C ^{[1
]}

Jensen, LJ ^{[1
]}

Ussery, DW ^{[1
]}

机构：

[1] Tech Univ Denmark, Dept Biotechnol, Ctr Biol Sequence Anal, DK-2800 Lyngby, Denmark

来源：

GENETICA | 2000年 / 108卷 / 01期

关键词：

base composition; Escherichia coli; pathogenicity islands; Salmonella typhimurium DT104; Yersenia pestis;

D O I：

10.1023/A:1004091626474

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We show here how pathogenicity islands can be analysed using GenomeAtlases, which is a method for visualising repeats, DNA structural characteristics, and base composition of chromosomes and plasmids. We have applied this method to the E. coli plasmid pO157, and the Y. pestis plasmid pPCP1. In both cases pathogenic genes were shown to differ in A+T content and structural properties. Furthermore, examination of an antibiotic resistance gene cluster from S. typhimurium showed that the same was true for genes encoding antibiotic resistance.

引用

页码：47 / 51

页数：5

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