An efficient method for the synthesis of 3-cyano-6-hydroxy-2(1H)-pyridinones under microwave irradiation and solvent-free conditions

被引：14

作者：

Balalaie, S

Kowsari, E

Hashtroudi, MS

机构：

[1] KN Toosi Univ Technol, Dept Chem, Tehran, Iran

[2] Mat & Energy Res Ctr, Energy & Environm Dept, Tehran, Iran

来源：

MONATSHEFTE FUR CHEMIE | 2003年 / 134卷 / 03期

关键词：

solvent-free organic synthesis; microwave chemistry; cyclocondensation; 2-pyridinones;

D O I：

10.1007/s00706-002-0551-2

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three component condensation of alkylacetoacetates, primary amines, and alkyl cyanoacetates catalyzed by solid supports under microwave irradiation gave N-alkyl 3-cyano-6-hydroxy-2(1H)-pyridinones with high yields. Upon carrying out the reaction under the same condition on acidic alumina, zeolite HY, silica gel, and montmorillonite K-10, the best yields were achieved by silica gel.

引用

页码：453 / 456

页数：4

共 33 条

[11] ELGUERO J, 1976, TAUTOMERISM HETEROCY, V1, pP106
[12] GMAJ J, 1991, Patent No. 150312
[13] HATTORI Y, 1988, Patent No. 63304267
[14] IMAI A, 1986, Patent No. 6371392
[15] KARASAWA A, 1991, Patent No. 361085
[16] KATRIZKY AR, 1995, J HETEROCYCLIC CHEM, P1007
[17] MURATA J, 1990, Patent No. 2243395
[18] MURATA Y, 1986, Patent No. 61244595
[19] Synthesis of heteroaryl pyridone methine dyes
Ni, AW
Chen, KC
Tian, H
[J]. DYES AND PIGMENTS, 2001, 50 (01) : 13 - 19
[20] NIWA T, 1985, Patent No. 60152563

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