Helicase structures: a new twist on DNA unwinding

被引：22

作者：

Marians, KJ

机构：

[1] Molecular Biology Program, Mem. Sloan-Kettering Cancer Center, New York, NY 10021

来源：

STRUCTURE | 1997年 / 5卷 / 09期

关键词：

D O I：

10.1016/S0969-2126(97)00263-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The crystal structures of two members of the SF1 family of helicases, Rep and PcrA, and one member of the SF2 family of helicases, the HCV RNA helicase, have recently been solved. These structures illuminate the roles of the conserved helicase motifs in catalytic function and offer clues as to how these proteins can translocate along DNA.

引用

页码：1129 / 1134

页数：6