Miniature near-infrared dual-axes confocal microscope utilizing a two-dimensional microelectromechanical systems scanner

被引:77
作者
Liu, Jonathan T. C. [1 ]
Mandella, Michael J.
Ra, Hyejun
Wong, Larry K.
Solgaard, Olav
Kino, Gordon S.
Piyawattanametha, Wibool
Contag, Christopher H.
Wang, Thomas D.
机构
[1] Stanford Univ, Edward L Ginzton Lab, Stanford, CA 94305 USA
[2] Stanford Univ, James H Clark Ctr Biomed Engn & Sci, Stanford, CA 94305 USA
关键词
D O I
10.1364/OL.32.000256
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
The first, to our knowledge, miniature dual-axes confocal microscope has been developed, with an outer diameter of 10 mm, for subsurface imaging of biological tissues with 5-7 mu m resolution. Depth-resolved en face images are obtained at 30 frames per second, with a field of view of 800 x 100 Am, by employing a two-dimensional scanning microelectromechanical systems mirror. Reflectance and fluorescence images are obtained with a laser source at 785 nm, demonstrating the ability to perform real-time optical biopsy. (c) 2007 Optical Society of America.
引用
收藏
页码:256 / 258
页数:3
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