Host cell death machinery as a target for bacterial pathogens

被引:27
作者
Boehme, Linda [1 ]
Rudel, Thomas [1 ]
机构
[1] Univ Wurzburg, Biozentrum, Lehrstuhl Mikrobiol, D-97074 Wurzburg, Germany
关键词
Programmed cell death (PCD); Apoptosis; Caspases; Bcl-2 like proteins; Survival pathways; Bacterial infection; NF-KAPPA-B; TRACHOMATIS-INFECTED CELLS; RICKETTSIA-RICKETTSII INFECTION; STAUROSPORINE-INDUCED APOPTOSIS; HUMAN NEUTROPHIL APOPTOSIS; HUMAN URETHRAL EPITHELIUM; NEISSERIA-GONORRHOEAE; PROTECTS CELLS; PORIN PORB; INHIBITS APOPTOSIS;
D O I
10.1016/j.micinf.2009.08.014
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Elimination of infected cells via programmed cell death plays a fundamental role in the defense of multicellular organisms against bacteria, viruses, and parasites Several pathogens have therefore evolved sophisticated strategies to modulate the host cell death programme for their survival. This review aims to summarize recent findings on how bacterial pathogens interfere with the host cell death apparatus. (C) 2009 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:1063 / 1070
页数:8
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