Transcranial magnetic stimulation for migraine: Clinical effects

被引：81

作者：

Clarke B.M. ^{[1
,2
]}

Upton A.R.M. ^{[1
]}

Kamath M.V. ^{[1
]}

Al-Harbi T. ^{[1
]}

Castellanos C.M. ^{[1
]}

机构：

[1] Division of Neurology, McMaster University, Hamilton, ON L8N 3Z5

[2] Hamilton Health Sciences Centre, Department of Clinical Neurology, McMaster University, Hamilton, ON L8N 3Z5

来源：

The Journal of Headache and Pain | 2006年 / 7卷 / 5期

基金：

加拿大自然科学与工程研究理事会;

关键词：

Migraine; Pain; Transcranial magnetic stimulation;

D O I：

10.1007/s10194-006-0329-8

中图分类号：

学科分类号：

摘要：

The objective was to assess the impact of transcranial magnetic stimulation (TMS) on pain and the autonomic nervous system (ANS) in migraine. Fortytwo people [mean age 41.43 ± 11.69 (SD) years, 36 females] were randomised into high vs. low TMS stimulation groups and received 2 brief pulses of TMS. Thirty-three (33/42) individuals had heart-rate variability assessed, before and after stimulation. No group effects were found. Pain decreased by 75%; 32% of people after 1 treatment reported no headache after 24 h. Mean heart rate decreased from 79.05 ± 10.27 to 72.89 ± 11.35 beats/min. The low-frequency (LF) and the high-frequency (HF) areas derived from power spectral analyses increased [mean 6522 ± 1277 to 8315 ± 1009 beats/min2 (LF) (p=0.001) and mean 5600 ± 1568 to 8755 ± 3071 beats/min2 (HF) (p=0.001)]. The LF:HF ratio decreased from mean 1.31 ± 0.51 to 1.13 ± 0.48 (NS). TMS produces immediate, sustained reductions in pain and modification of the ANS. © Springer-Verlag Italia 2006.

引用

页码：341 / 346

页数：5