ADHD characteristics: I. Concurrent co-morbidity patterns in children & adolescents

被引：122

作者：

Elia J. ^{[1
,2
]}

Ambrosini P. ^{[3
]}

Berrettini W. ^{[2
]}

机构：

[1] Department of Child and Adolescent Psychiatry, The Children's Hospital of Philadelphia, Philadelphia, PA

[2] Department of Psychiatry, The University of Pennsylvania, Philadelphia, PA

[3] Department of Psychiatry, Drexel University College of Medicine, Philadelphia, PA

来源：

Child and Adolescent Psychiatry and Mental Health | / 2卷 / 1期

关键词：

Generalize Anxiety Disorder; Oppositional Defiant Disorder; ADHD Symptom; ADHD Child; Oppositional Defiant Disorder;

D O I：

10.1186/1753-2000-2-15

中图分类号：

学科分类号：

摘要：

Objective: 342 Caucasian subjects with attention deficit/hyperactivity disorder (ADHD) were recruited from pediatric and behavioral health clinics for a genetic study. Concurrent comorbidity was assessed to characterize the clinical profile of this cohort. Methods: Subjects 6 to 18 years were diagnosed with the Schedule for Affective Disorders & Schizophrenia for School aged Children (K-SADS-P IVR). Results: The most prevalent diagnoses co-occurring with ADHD were Oppositional Defiant Disorder (ODD) (40.6%), Minor Depression/Dysthymia (MDDD) (21.6%), and Generalized Anxiety Disorder (GAD) (15.2%). In Inattentive ADHD (n = 106), 20.8% had MDDD, 20.8% ODD, and 18.6% GAD; in Hyperactive ADHD (n = 31) 41.9% had ODD, 22.2% GAD, and 19.4% MDDD. In Combined ADHD, (n = 203), 50.7% had ODD, 22.7% MDDD and 12.4% GAD. MDDD and GAD were equally prevalent in the ADHD subtypes but, ODD was significantly more common among Combined and Hyperactive ADHD compared to Inattentive ADHD. The data suggested a subsample of Irritable prepubertal children exhibiting a diagnostic triad of ODD, Combined ADHD, and MDDD may account for the over diagnosing of Bipolar Disorder. Conclusion: Almost 2/3rd of ADHD children have impairing comorbid diagnoses; Hyperactive ADHD represents less than 10% of an ADHD sample; ODD is primarily associated with Hyperactive and Combined ADHD; and, MDDD may be a significant morbidity for ADHD youths from clinical samples. © 2008 Elia et al; licensee BioMed Central Ltd.

引用

共 33 条

[31]

Vance A., Sanders M., Arduca Y., Dysthymic disorder contributes to oppositional defiant behaviour in children with Attention Deficit Hyperactivity Disorder, combined type (ADHD-CT), J Affect Disord, 86, 2-3, pp. 329-333, (2005)

[32]

Masi G., Perugi G., Millepiedi S., Mucci M., Pari C., Pfanner C., Berloffa S., Toni C., Clinical implications of DSM-IV subtyping of bipolar disorders in referred children and adolescents, J Am Acad Child Adolesc Psychiatry, 46, 10, pp. 1299-1306, (2007)

[33]

Pliszka S.R., Patterns of psychiatric comorbidity with attention-deficit/hyperactivity disorder, Child Adolesc Psychiatr Clin N Am, 9, 3, pp. 525-540, (2000)

← 1 2 3 4 →