Nipah virus encephalitis

被引：11

作者：

Tan C.-T. ^{[1
]}

Chua K.-B. ^{[1
]}

机构：

[1] Department of Medicine, University of Malaya

来源：

Current Infectious Disease Reports | 2008年 / 10卷 / 4期

关键词：

Encephalitis; Viral Encephalitis; Emerg Infect; Nipah Virus; Hendra Virus;

D O I：

10.1007/s11908-008-0051-6

中图分类号：

学科分类号：

摘要：

Nipah virus was first discovered in 1999, after a severe outbreak of viral encephalitis among pig farm workers in Malaysia. The disease is thought to spread from Pteropus bats to pigs and then to humans following close contact. The reported mortality rate in this outbreak was 40%. The main necropsy finding in patients with Nipah virus encephalitis was disseminated microinfarction associated with vasculitis and direct neuronal involvement. Relapse of encephalitis was seen in 10% of those who survived the initial illness. Since that initial report, recurrent outbreaks of Nipah virus encephalitis have been seen in Bangladesh and West Bengal, India. These outbreaks occurred between January and May, with Pteropus giganteus as a reservoir of the virus. In Bangladesh, the virus probably spread directly from bats to humans - with human to human spread as another important mode of infection - and the mortality rate was 70%. Copyright © 2008 by Current Medicine Group LLC.

引用

页码：315 / 320

页数：5

共 54 条

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