Management and prevention of stroke associated with elevated homocysteine

被引:21
作者
Peter J. Kelly
Karen L. Furie
机构
[1] Massachusetts General Hospital,Stroke Service, Department of Neurology
关键词
Folic Acid; Ischemic Stroke; Homocysteine; Cerebral Venous Thrombosis; Homocystinuria;
D O I
10.1007/s11936-002-0016-2
中图分类号
学科分类号
摘要
Observational data from prospective and retrospective studies indicate that elevated homocyst(e)ine (Hcy) is associated with preclinical markers of cerebrovascular disease and ischemic stroke.
引用
收藏
页码:363 / 371
页数:8
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  • [1] McCully K(1969)Vascular pathology of homocysteinemia: implications for the pathogenesis of atherosclerosis Am J Pathol 56 111-128
  • [2] Welch G(1998)Mechanisms of disease: homocysteine and atherothrombosis N Engl J Med 338 1042-1050
  • [3] Loscalzo J(2000)Homocysteine and its disulfide derivatives: a suggested consensus terminology Arterioscler Thromb Vasc Biol 20 1704-1706
  • [4] Mudd SH(1993)Vitamin status and intake as primary determinants of homocysteinemia in an elderly population JAMA 270 2693-2698
  • [5] Finkelstein JD(2000)Genetic modulation of homocysteinemia Semin Thromb Hemost 26 255-261
  • [6] Refsum H(1997)Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans Circulation 95 1119-1121
  • [7] Selhub J(1993)Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. The Atherosclerosis Risk in Communities Study Circulation 87 1107-1113
  • [8] Jacques PF(1995)Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis N Engl J Med 332 286-291
  • [9] Wilson PWF(2000)Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiologic subtypes of ischemic stroke Stroke 31 1069-1075
  • [10] Rozen R(1997)Hyperhomocysteinemia in black patients with cerebral thrombosis Q J Med 90 635-639