The primate working memory networks

被引:141
作者
Constantinidis C. [1 ,3 ]
Procyk E. [2 ]
机构
[1] Wake Forest University, School of Medicine, Winston-Salem, NC
[2] Inserm U371, Inst. Federatif Neurosci. de Lyon, Bron
[3] Dept. of Neurobiology and Anatomy, Wake Forest University, School of Medicine, Winston-Salem, NC 27157-1010, Medical Center Blvd.
关键词
Prefrontal Cortex; Receptive Field; Posterior Parietal Cortex; Macaque Monkey; Experimental Brain Research;
D O I
10.3758/CABN.4.4.444
中图分类号
学科分类号
摘要
Working memory has long been associated with the prefrontal cortex, since damage to this brain area can critically impair the ability to maintain and update mnemonic information. Anatomical and physiological evidence suggests, however, that the prefrontal cortex is part of a broader network of interconnected brain areas involved in working memory. These include the parietal and temporal association areas of the cerebral cortex, cingulate and limbic areas, and subcortical structures such as the mediodorsal thalamus and the basal ganglia. Neurophysiological studies in primates confirm the involvement of areas beyond the frontal lobe and illustrate that working memory involves parallel, distributed neuronal networks. In this article, we review the current understanding of the anatomical organization of networks mediating working memory and the neural correlates of memory manifested in each of their nodes. The neural mechanisms of memory maintenance and the integrative role of the prefrontal cortex are also discussed. Copyright 2004 Psychonomic Society, Inc.
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页码:444 / 465
页数:21
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