Protective effect of secoisolariciresinol diglucoside against streptozotocin-induced diabetes and its mechanism

被引：7

作者：

Kailash Prasad

Subrahmanyam Mantha

Alister Muir

Neil Westcott

机构：

[1] University of Saskatchewan,Department of Physiology, College of Medicine

[2] Agriculture and Agri-Food Canada,undefined

来源：

Molecular and Cellular Biochemistry | 2000年 / 206卷

关键词：

oxygen free radicals; streptozotocin; diabetes; secoisolariciresinol diglucoside; malondialdehyde; pancreatic chemiluminescence;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Objectives: Reactive oxygen species (ROS) have been implicated in the development of streptozotocin (STZ)-induced diabetes mellitus. Secoisolariciresinol diglucoside (SDG) isolated from flaxseed is an antioxidant. An investigation was made of the effects of SDG on the development of STZ-induced diabetes in rat, to determine if SDG can prevent/reduce the development of diabetes and if this prevention/reduction is associated with reduction in oxidative stress.

引用

页码：141 / 150

页数：9

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