Tea polyphenols benefit vascular function

被引：62

作者：

Yung L.M. ^{[1
]}

Leung F.P. ^{[1
]}

Wong W.T. ^{[1
]}

Tian X.Y. ^{[1
]}

Yung L.H. ^{[1
]}

Chen Z.Y. ^{[2
]}

Yao X.Q. ^{[1
]}

Huang Y. ^{[1
]}

机构：

[1] Institute of Vascular Medicine, Department of Physiology, Chinese University of Hong Kong, Shatin, NT

[2] Department of Biochemistry, Chinese University of Hong Kong, Hong Kong

来源：

Inflammopharmacology | 2008年 / 16卷 / 5期

关键词：

Antioxidant effect; Atherosclerosis; Endothelial dysfunction; Hypertension; Hypolipidemic effect; Nitric oxide; Tea polyphenols; Vasorelaxant effect;

D O I：

10.1007/s10787-008-8022-y

中图分类号：

学科分类号：

摘要：

Tea, the most popular beverage worldwide, is consumed in three basic forms; green tea, black tea and oolong tea. Tea contains over 4,000 chemicals some of which are bioactive. In recent years there has been a mounting interest in understanding the cardiovascular and metabolic benefits of polyphenolic flavonoids in tea, which can be used as a supplement among patients. Diverse cardioprotective effects of consuming tea or tea polyphenols have been described on pathological conditions, e. g. hypertension, atherosclerosis, diabetics, hypercholesterolemia, obesity, and are attributed to antioxidative, anti-thrombogenic, anti-inflammatory, hypotensive and hypocholesterolemic properties of tea polyphenols. This review focuses on cardiovascular benefits of tea polyphenols based on in vitro and in vivo studies on experimental animal models and on studies of human subjects in four areas: (1) vasorelaxant effect; (2) protective effect against endothelial dysfunction; (3) antioxidant effect and (4) hypolipidemic effect. We will briefly discuss the effects of tea on atherosclerosis and hypertension. © 2008 Birkhäuser Verlag.

引用

页码：230 / 234

页数：4

共 38 条

[1]

Ardalan M.R., Tarzamni M.K., Shoja M.M., Et al., Black tea improves endothelial function in renal transplant recipients, Transplant Proc, 39, pp. 1139-1142, (2007)

[2]

Bryans J.A., Judd P.A., Ellis P.A., The effect of consuming instant black tea on postprandial plasma glucose and insulin concentrations in healthy humans, J. Am. Coll. Nutr, 26, pp. 471-477, (2007)

[3]

Cao H., Kelly M.A., Kari F., Et al., Green tea increases antiinflammatory tristetraprolin and decreases pro-inflammatory tumor necrosis factor mRNA levels in rats, J. Inflamm (Lond), 4, (2007)

[4]

Chan P.T., Fong W.P., Cheung Y.L., Et al., Jasmine green tea epicatechins are hypolipidemic in hamsters (Mesocricetus auratus) fed a high fat diet, J Nutr, 129, pp. 1094-1101, (1999)

[5]

Cheng X.W., Kuzuya M., Sasaki T., Et al., Green tea catechins inhibit neointimal hyperplasia in a rat carotid arterial injury model by TIMP-2 overexpression, Cardiovasc. Res, 62, pp. 594-602, (2004)

[6]

Graham H.N., Green tea composition, consumption, and polyphenol chemistry, Prev Med, 21, pp. 334-350, (1992)

[7]

Grundy S.M., Cholesterol and coronary heart disease. A new era, JAMA, 256, pp. 2849-2858, (1986)

[8]

Hertog M.G., Feskens E.J., Hollman P.C., Et al., Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study, Lancet, 342, pp. 1007-1011, (1993)

[9]

Hodgson J.M., Puddey I.B., Burke V., Et al., Effects on blood pressure of drinking green and black tea, J. Hypertens, 17, pp. 457-463, (1994)

[10]

Hodgson J.M., Puddey I.B., Burke V., Et al., Regular ingestion of black tea improves brachial artery vasodilator function, Clin. Sci. (Lond), 102, pp. 195-201, (2002)

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