In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng

被引:12
作者
Wei Wang
Yuqing Zhao
Elizabeth R. Rayburn
Donald L. Hill
Hui Wang
Ruiwen Zhang
机构
[1] University of Alabama at Birmingham,Department of Pharmacology and Toxicology, Division of Clinical Pharmacology, Cancer Pharmacology Laboratory
[2] University of Alabama at Birmingham,Comprehensive Cancer Center
[3] Shenyang Pharmaceutical University,Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences
[4] Chinese Academy of Sciences,undefined
来源
Cancer Chemotherapy and Pharmacology | 2007年 / 59卷
关键词
Chemical structure; Anticancer; Structure–activity relationship;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:589 / 601
页数:12
相关论文
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  • [31] Slepyan LI(1991)Inhibitory effects of ginsenoside Rh Planta Med 57 125-128
  • [32] Davydov VV(1994) on tumor growth in nude mice bearing human ovarian cancer cells Biol Pharmaceut Bull 17 635-639
  • [33] Chang YS(2001)Control of phenotypic expression of cultured B16 melaonma cells by plant glycosides J Korean Med Sci 16 S28-S37
  • [34] Seo EK(2002)20( Am J Chinese Med 30 483-494
  • [35] Gyllenhaal C(1997))-Protopanaxatriol, one of ginsenoside metabolites, inhibits inducible nitric oxide synthase and cyclooxygenase-2 expressions through inactivation of nuclear factor-kappaB in RAW 264.7 macrophages stimulated with lipopolysaccharide Oncol Res 9 411-417
  • [36] Block KI(1999)Plant-glycoside modulation of cell surface related to control of differentiation in cultured B16 melanoma cells Proc Natl Acad Sci USA 96 13989-13994
  • [37] Chen YJ(2003)Activation of caspase-3 protease via a Bcl-2-insensitive pathway during the process of ginsenoside Rh Prostate 54 194-205
  • [38] Wang HY(1982)-induced apoptosis Plant Med 1982 45 167-171
  • [39] Xu SX(2001)Structure–function relationship exists for ginsenosides in reducing cell proliferation and inducing apoptosis in the human leukemia (THP-1) cell line J Korean Med Sci 16 S61-S65
  • [40] Cheng YJ(2005)Inhibition of mutagenesis and transformation by root extracts of Panax ginseng in vitro Acta Pharmacol Sin 26 1104-1110