Cardiovascular disease: much more aggressive in patients with type 2 diabetes.

被引：25

作者：

Chiquette E. ^{[1
]}

Chilton R. ^{[1
]}

机构：

[1] University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, 78284-7872, TX

来源：

Current Atherosclerosis Reports | 2002年 / 4卷 / 2期

关键词：

Coronary Artery Bypass Graft; Pravastatin; United Kingdom Prospective Diabetes Study; Left Internal Mammary Artery; Silent Ischemia;

D O I：

10.1007/s11883-002-0037-z

中图分类号：

学科分类号：

摘要：

It is estimated that 80% of individuals with type 2 diabetes die of coronary heart disease. Several factors have been found to contribute to the accelerated atherosclerosis present in diabetic patients. These include hyperglycemia-induced endothelial cell dysfunction, impaired fibrinolysis, increased platelet aggregation, and dysfunctional arterial remodeling. The evidence supports that a healthy lifestyle, statin drugs, angiotensin-converting enzyme inhibitors, and aspirin can modify these factors and slow the atherosclerosis process observed in type 2 diabetes. Because of the high prevalence of cardiovascular disease in people with type 2 diabetes, early cardiac testing is indicated. The optimal strategy for coronary revascularization in diabetic patients remains controversial and is discussed in detail in this review.

引用

页码：134 / 142

页数：8

共 168 条

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