Pathogenesis of Parkinson’s disease: oxidative stress, environmental impact factors and inflammatory processes帕金森病的发病机理: 氧化应激, 环境影响因素与神经炎症

被引：60

作者：

Hong Yuan

Jing-Chen Zheng

Ping Liu

Shao-Feng Zhang

Jian-Yang Xu

Li-Min Bai

机构：

[1] the General Hospital of Chinese People’s Armed Police Forces,Department of Integrated Traditional Chinese and Western Medicine

[2] Harbin Medical University,Department of Immunology

[3] Beijing University of Chinese Medicine,Department of Anatomy

来源：

Neuroscience Bulletin | 2007年 / 23卷 / 2期

关键词：

pathogenesis; Parkinson’s disease; oxidative stress; neurogenic inflammation; environmental impact; 发病机理; 帕金森病; 氧化应激; 神经炎症; 环境影响; R742.5;

D O I：

10.1007/s12264-007-0018-x

中图分类号：

学科分类号：

摘要：

Current hypothesis of neuronal degeneration in Parkinson’s disease (PD) have been proposed, including formation of free radicals and oxidative stress, mitochondrial dysfunction, excitotoxicity, trophic factor deficiency, inflammatory processes, genetic factors, environmental impact factors, toxic action of nitric oxide, apoptosis, and so on. This review mainly discussed oxidative stress, environmental impact factors, and inflammatory processes in PD.

引用

页码：125 / 130

页数：5

共 95 条

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