Pathogenesis of Parkinson’s disease: oxidative stress, environmental impact factors and inflammatory processes帕金森病的发病机理: 氧化应激, 环境影响因素与神经炎症

Current hypothesis of neuronal degeneration in Parkinson’s disease (PD) have been proposed, including formation of free radicals and oxidative stress, mitochondrial dysfunction, excitotoxicity, trophic factor deficiency, inflammatory processes, genetic factors, environmental impact factors, toxic action of nitric oxide, apoptosis, and so on. This review mainly discussed oxidative stress, environmental impact factors, and inflammatory processes in PD.