Comparison of limbal-conjunctival autograft and intraoperative 0.02% mitomycin-C for treatment of primary pterygium

被引：22

作者：

Akinci A. ^{[1
]}

Zilelioglu O. ^{[1
]}

机构：

[1] Vitreoretinal Surgery Unit, Ulucanlar Eye Hospital, Ankara, Dikmen, Ulucanlar Cad.

来源：

International Ophthalmology | 2007年 / 27卷 / 5期

关键词：

LCAG; MMC; Primary pterygia;

D O I：

10.1007/s10792-007-9034-0

中图分类号：

学科分类号：

摘要：

Purpose: To compare the outcomes of use of intraoperative 0.02% mitomycin-C (MMC) and limbal-conjunctival autograft (LCAG) for treatment of primary pterygia. Material and method: One hundred and twelve eyes of eighty patients with primary pterygia were randomly treated either by intraoperative 0.02% MMC for 5 min or LCAG. Recurrence (defined as fibrovascular tissue invading the cornea >1.5 mm) and complications were evaluated. Results: Fifty-two eyes were included in the MMC group and sixty in the LCAG group. Recurrence occurred in three eyes (5.76%) in the MMC group and in two eyes (3.33%) in the LCAG group. This difference between recurrence in the two groups was not statistically significant (P > 0.05). Incidence of complications such as conjunctival cysts, symblephara, conjunctival hyperemia, and subconjunctival hemorrhage was similar in both groups (P > 0.05) whereas corneal epithelial defects (CED), irritation, lacrimation, and photophobia were more common in the MMC group (P < 0.05). Conclusion: Simple excision then intraoperative use of 0.02% (MMC) for 5 min or LCAG are similarly successful in the treatment of primary pterygia. Some complications, for example irritation, lacrimation, photophobia, and CED are more common when simple excision is followed by MMC. © Springer Science+Business Media, Inc. 2007.

引用

页码：281 / 285

页数：4

共 23 条

[11]

Young A.L., Leung G.Y.S., Wong A.K.K., A randomised trial comparing 0.02% mitomycin C and limbal conjunctival autograft after excision of primary pterygium, Br J Ophthalmol, 88, 8, pp. 995-997, (2004)

[12]

Al Fayez M.F., Limbal versus conjunctival autograft transplantation for advanced and recurrent pterygium, Ophthalmology, 109, 9, pp. 1752-1755, (2002)

[13]

Rao S.K., Lekha T., Mukesh B.N., Et al., Conjunctival-limbal autografts for primary and recurrent pterygia: Technique and results, Ind J Ophthalmol, 46, 4, pp. 203-209, (1998)

[14]

Barraquer J.I., Binder P.S., Buxton J.N., Et al., Etiology and treatment of pterygium, Transactions of the New Orleans Academy of Ophthalmology, pp. 167-178, (1980)

[15]

Chen P.P., Ariyasu R.G., Kaza V., Et al., A randomized trial comparing mitomycin C and conjunctival autograft after excision of primary pterygium, Am J Ophthalmol, 120, 2, pp. 151-160, (1995)

[16]

Kenyon K.R., Tseng S.C.G., Limbal autograft transplantation for ocular surface disorders, Ophthalmology, 96, 5, pp. 709-723, (1989)

[17]

Gris O., Guell J.L., del Campo Z., Limbal-conjunctival autograft transplantation for the treatment of recurrent pterygium, Ophthalmology, 107, 2, pp. 270-273, (2000)

[18]

Hardman J.G., Limbird L.E., Molinoff P.B., Et al., Goodman and Gilman's Las Bases Farmacologicas De La Therapeutica, pp. 1347-1348, (1996)

[19]

Cheng H.C., Tseng S.H., Kao P.L., Et al., Low-dose intraoperative mitomycin C as chemoadjuvant for pterygium surgery, Cornea, 20, 1, pp. 24-29, (2001)

[20]

Cardillo J.A., Alves M.R., Ambroso L.E., Et al., Single intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery, Ophthalmology, 102, 12, pp. 1949-1952, (1995)

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