Lessons Learned from Gene Targeting and Transgenesis for Adrenal Physiology and Disease

Weinshenker D., Rust N.C., Miller N.S., Palmiter R.D., Ethanol-associated behaviors of mice lacking norepinephrine, J Neurosci, 20, pp. 3157-3164, (2000)

Buttner A., Hejgaard K.C., Haidan A., Eisenhofer G., Pacak K., Scherbaum W.A., Chrousos G.P., Bornstein S.R., A new role for brain epinephrine linking aggression to metabolic risk factors, Exp Clin Endocrinol Diabetes, 108, pp. S111-S111

Cases O., Seif I., Grimsby J., Gaspar P., Chen K., Pournin S., Muller U., Aguet M., Babinet C., Shih J.C., Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA, Science, 268, pp. 1763-1766, (1995)

Stenzel-Poore M.P., Heinrichs S.C., Rivest S., Koob G.F., Vale W.W., Overproduction of corticotropin-releasing factor in transgenic mice: A genetic model of anxiogenic behavior, J Neurosci, 14, pp. 2579-2584, (1994)

Heinrichs S.C., Min H., Tamraz S., Carmouche M., Boehme S.A., Vale W.W., Anti-sexual and anxiogenic behavioral consequences of corticotropin-releasing factor overexpression are centrally mediated, Psychoneuroendocrinology, 22, pp. 215-224, (1997)

Kishimoto T., Radulovic J., Radulovic M., Lin C.R., Schrick C., Hooshmand F., Hermanson O., Rosenfeld M.G., Spiess J., Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2, Nat Genet, 24, pp. 415-419, (2000)

Dunn A.J., Swiergiel A.H., Behavioral responses to stress are intact in CRF-deficient mice, Brain Res, 845, pp. 14-20, (1999)

Yano H., Readhead C., Nakashima M., Ren S.-G., Melmed S., Pituitary-directed leukemia inhibitory factor transgene causes Cushings syndrome: Neuro-immune-endocrine modulation of pituitary development, Mol Endocrinol, 12, pp. 1708-1720, (1998)

Raber J., O'Shea R.D., Bloom F.E., Campbell I.L., Modulation of hypothalamic-pituitary-adrenal function by transgenic expression of interleukin-6 in the CNS of mice, J Neurosci, 17, pp. 9473-9480, (1997)

Turnbull A.V., Smith G.W., Lee S., Vale W.W., Lee K.F., Rivier C., CRF type I receptor-deficient mice exhibit a pronounced pituitary-adrenal response to local inflammation, Endocrinology, 140, pp. 1013-1017, (1999)

Weinshenker D., Rust N.C., Miller N.S., Palmiter R.D., Ethanol-associated behaviors of mice lacking norepinephrine, J Neurosci, 20, pp. 3157-3164, (2000)

Buttner A., Hejgaard K.C., Haidan A., Eisenhofer G., Pacak K., Scherbaum W.A., Chrousos G.P., Bornstein S.R., A new role for brain epinephrine linking aggression to metabolic risk factors, Exp Clin Endocrinol Diabetes, 108, pp. S111-S111

Cases O., Seif I., Grimsby J., Gaspar P., Chen K., Pournin S., Muller U., Aguet M., Babinet C., Shih J.C., Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA, Science, 268, pp. 1763-1766, (1995)

Stenzel-Poore M.P., Heinrichs S.C., Rivest S., Koob G.F., Vale W.W., Overproduction of corticotropin-releasing factor in transgenic mice: A genetic model of anxiogenic behavior, J Neurosci, 14, pp. 2579-2584, (1994)

Heinrichs S.C., Min H., Tamraz S., Carmouche M., Boehme S.A., Vale W.W., Anti-sexual and anxiogenic behavioral consequences of corticotropin-releasing factor overexpression are centrally mediated, Psychoneuroendocrinology, 22, pp. 215-224, (1997)

Kishimoto T., Radulovic J., Radulovic M., Lin C.R., Schrick C., Hooshmand F., Hermanson O., Rosenfeld M.G., Spiess J., Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2, Nat Genet, 24, pp. 415-419, (2000)

Dunn A.J., Swiergiel A.H., Behavioral responses to stress are intact in CRF-deficient mice, Brain Res, 845, pp. 14-20, (1999)

Yano H., Readhead C., Nakashima M., Ren S.-G., Melmed S., Pituitary-directed leukemia inhibitory factor transgene causes Cushings syndrome: Neuro-immune-endocrine modulation of pituitary development, Mol Endocrinol, 12, pp. 1708-1720, (1998)

Raber J., O'Shea R.D., Bloom F.E., Campbell I.L., Modulation of hypothalamic-pituitary-adrenal function by transgenic expression of interleukin-6 in the CNS of mice, J Neurosci, 17, pp. 9473-9480, (1997)

Turnbull A.V., Smith G.W., Lee S., Vale W.W., Lee K.F., Rivier C., CRF type I receptor-deficient mice exhibit a pronounced pituitary-adrenal response to local inflammation, Endocrinology, 140, pp. 1013-1017, (1999)