Diabetes and stroke: Part one - Risk factors and pathophysiology

被引：22

作者：

Baliga B.S. ^{[1
]}

Weinberger J. ^{[1
]}

机构：

[1] Division of Endocrinology and Metabolism, North General Hospital, New York, NY 10031

来源：

Current Cardiology Reports | 2006年 / 8卷 / 1期

关键词：

Metabolic Syndrome; Ischemic Stroke; Hyperglycemia; Hemorrhagic Stroke; Nondiabetic Subject;

D O I：

10.1007/s11886-006-0006-1

中图分类号：

学科分类号：

摘要：

Diabetes is a major risk factor for stroke and is associated with an increase in overall stroke mortality. The metabolic syndrome associated with insulin resistance is also a significant risk factor for stroke. The etiology of stroke in diabetics is frequently microvascular disease from fibrinoid necrosis, which causes small subcortical infarcts designated as lacunar strokes. Diabetics also have an increased incidence of large vessel intracranial vascular disease. Although strict control of blood sugar has not been shown to reduce the overall incidence of stroke in diabetics, careful management of other associated risk factors, particularly hypercholesterolemia and hypertension, are imperative for the prevention of stroke in diabetic patients. Copyright © 2006 by Current Science Inc.

引用

页码：23 / 28

页数：5

共 80 条

[41]

Haheim L.L., Holme I., Hjermann I., Leren P., Nonfasting serum glucose and the risk of fatal stroke in diabetic and nondiabetic subjects. 18-year follow-up of the Oslo Study, Stroke, 26, pp. 774-777, (1995)

[42]

Lowe L.P., Liu K., Greenland P., Et al., Diabetes, asymptomatic hyperglycemia, and 22-year mortality in black and white men, Diabetes Care, 20, pp. 163-169, (1997)

[43]

Staaf G., Lindgren A., Norrving B., Pure motor stroke from presumed lacunar infarct. Long-term prognosis for survival and risk of recurrent stroke, Stroke, 32, pp. 2592-2596, (2001)

[44]

Christensen H., Boysen G., Johannesen H., Et al., Deteriorating ischaemic stroke. cytokines, soluble cytokine receptors, ferritin, systemic blood pressure, body temperature, blood glucose, diabetes, stroke severity, and CT infarction-volume as predictors of deteriorating ischaemic stroke, J Neurol Sci, 201, pp. 1-7, (2002)

[45]

Williams L.S., Rotich J., Qi R., Et al., Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke, Neurology, 59, pp. 67-71, (2002)

[46]

Woo J., Lam C.W.K., Kay R., Et al., The influence of hyperglycemia and diabetes mellitus on immediate and 3-month morbidity and mortality after acute stroke, Arch Neurol, 47, pp. 1174-1177, (1990)

[47]

Passero S., Ciacci G., Ulivelli M., The influence of diabetes and hyperglycemia on clinical course after intracerebral hemorrhage, Neurology, 25, pp. 1351-1356, (2003)

[48]

O'Neil P.A., Davies I., Fullerton K.J., Bennett D., Stress hormone and blood glucose response following acute stroke in the elderly, Stroke, 22, pp. 842-847, (1991)

[49]

Berger L., Hakim A.M., The association of hyperglycemia with cerebral edema in stroke, Stroke, 17, pp. 865-871, (1986)

[50]

Szczudlik A., Slowik A., Turaj W., Transient hyperglycemia in ischemic stroke patients, J Neurol Sci, 189, pp. 105-111, (2001)

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