New developments in the detection of vulnerable plaque.

被引：61

作者：

Naghavi M. ^{[1
]}

Madjid M. ^{[1
]}

Khan M.R. ^{[1
]}

Mohammadi R.M. ^{[1
]}

Willerson J.T. ^{[1
]}

Casscells S.W. ^{[1
]}

机构：

[1] Vulnerable Plaque Research Program, Division of Cardiology, Department of Internal Medicine, University of Texas-Houston Health Science Center and Texas Heart Institute, Houston, 77030, TX

来源：

Current Atherosclerosis Reports | 2001年 / 3卷 / 2期

关键词：

Acute Coronary Syndrome; Optical Coherence Tomography; Atherosclerotic Plaque; Electrical Impedance Imaging; Coronary Plaque;

D O I：

10.1007/s11883-001-0048-1

中图分类号：

学科分类号：

摘要：

Failure of coronary angiography (luminography) in prediction of future acute coronary syndromes has cast a shadow of doubt over the value of this old gold-standard technique. The fact that angiographically invisible or nonsignificant lesions cause the majority of acute coronary syndromes has driven scientists to develop new diagnostic methods. In this article, we review the ongoing worldwide research on both invasive techniques (such as intravascular angioscopy and colorimetry, ultrasound, thermography, optical coherence tomography, near infrared spectroscopy, Raman spectroscopy, fluorescence emission spectroscopy, elastography, magnetic resonance imaging and spectroscopy, nuclear immunoscintigraphy, electrical impedance imaging, vascular tissue doppler, and shear stress imaging) and noninvasive techniques (such as MRI, contrast-enhanced MRI with and without immunolabeled agents, electron beam computed tomography, multi-slice spiral / helical computed tomography, and nuclear imaging, including positron emission tomography). Each of these techniques and their potential combination holds promise for characterization of plaques responsible for acute coronary syndromes, namely vulnerable plaque.

引用

页码：125 / 135

页数：10

共 206 条

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