MicroRNAs as potential cancer therapeutics

被引：159

作者：

Trang P. ^{[1
,2
]}

Weidhaas J.B. ^{[2
]}

Slack F.J. ^{[1
]}

机构：

[1] Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT

[2] Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT

来源：

Oncogene | 2008年 / 27卷 / Suppl 2期

关键词：

Cancer; MicroRNAs; Profiling; Therapeutic; Tumor suppressor;

D O I：

10.1038/onc.2009.353

中图分类号：

学科分类号：

摘要：

MicroRNAs (miRNAs) have been shown to have an important role in various cellular processes, such as apoptosis, differentiation and development. Recent studies have shown that miRNAs are mis-expressed in human cancers where they can exert their effect as oncogenes or tumor suppressors. Here, we review the potential for using miRNAs as biomarkers for diagnosis, prognosis and cancer therapies. © 2009 Macmillan Publishers Limited. All rights reserved.

引用

页码：S52 / S57

页数：5

共 67 条

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