Vulvovaginal Candidiasis caused by non-albicans Candida species: New insights

被引：87

作者：

Kennedy M.A. ^{[1
]}

Sobel J.D. ^{[1
]}

机构：

[1] Division of Infectious Diseases, Wayne State University, School of Medicine, Detroit, MI

来源：

Current Infectious Disease Reports | 2010年 / 12卷 / 6期

关键词：

Candida albicans; Candida glabrata; Candida parapsilosis; Candida species; Non-albicans Candida; Vaginitis; Vulvovaginal candidiasis;

D O I：

10.1007/s11908-010-0137-9

中图分类号：

学科分类号：

摘要：

Non-albicans Candida species have increasingly been identified as the cause of vulvovaginitis. In vitro and in vivo data indicate that the various non-albicans Candida species identified in the lower genital tract differ considerably with regard to epidemiology, virulence or vaginal pathogenicity, and antimycotic drug susceptibility. Clinical experience indicates reduced virulence of these organisms in the lower genital tract, and their causal role in a symptomatic patient requires careful case-by-case determination rather than routine administration of antimycotic therapy. Accordingly, vaginal Candida isolates deserve species identification and consideration of pathogenic potential and antifungal susceptibility before therapeutic decisions are made. © 2010 Springer Science+Business Media, LLC.

引用

页码：465 / 470

页数：5

共 16 条

[1] Sobel J.D., Vulvovaginal candidosis, Lancet, 369, 9577, pp. 1961-1971, (2007)
[2] Vermitsky J.-P., Self M.J., Chadwick S.G., Trama J.P., Adelson M.E., Mordechai E., Gygax S.E., Survey of vaginal-flora Candida species isolates from women of different age groups by use of species-specific PCR detection, Journal of Clinical Microbiology, 46, 4, pp. 1501-1503, (2008)
[3] Mohanty S., Xess I., Hasan F., Et al., Prevalence and susceptibility to fluconazole of Candida species causing vulvovaginitis, Indian J Med Res, 126, pp. 216-219, (2007)
[4] Grigoriou O., Baka S., Makrakis E., Et al., Prevalence of clinical vaginal candidiasis in a university hospital and possible risk factors, Eur J Obstet Gynecol Reprod Biol, 126, pp. 121-125, (2006)
[5] Spinillo A., Capuzzo E., Gulminetti R., Marone P., Colonna L., Piazzi G., Prevalence of and risk factors for fungal vaginitis caused by non-albicans species, American Journal of Obstetrics and Gynecology, 176, 1, pp. 138-141, (1997)
[6] Fan S.R., Liu X.P., Li J.W., Clinical characteristics of vulvovaginal candidiasis and antifungal susceptibilities of Candida species isolates among patients in southern China from 2003 to 2006, J Obstet Gynaecol Res, 34, pp. 561-566, (2008)
[7] Ahmad N., Khan A.U., Prevalence of Candida species and potential risk factors for vulvovaginal candidiasis in Aligarh, India, Eur J Obstet Gynecol Reprod Biol, 144, pp. 68-71, (2009)
[8] Hettiarachchi N., Ashbee H.R., Wilson J.D., Prevalence and management of non-albicans vaginal candidiasis, Sex Trans Infect, 86, pp. 99-100, (2010)
[9] Agatensi L., Franchi F., Mondello F., Et al., Vaginopathic and proteolytic Candida species in outpatients attending a gynaecology clinic, J Clin Pathol, 44, pp. 826-830, (1991)
[10] Dennerstein G.J., Ellis D.E., Reed C.S., Bennett C.M., The pathogenicity of non-albicans yeasts in the vagina, J Low Genit Tract Dis, (2010)

← 1 2 →