Ventriculovascular coupling in systolic and diastolic heart failure.

被引：30

作者：

Fox J.M. ^{[1
]}

Maurer M.S. ^{[1
]}

机构：

[1] Clinical Cardiovascular Research Laboratory for the Elderly, Allen Pavilion of New York Presbyterian Hospital, Room, 3 Field West, Broadway, 10034, NY

来源：

Current Heart Failure Reports | 2005年 / 2卷 / 4期

关键词：

Total Peripheral Resistance; Systolic Heart Failure; Diastolic Heart Failure; Normal Ejection Fraction; Arterial Elastance;

D O I：

10.1007/BF02696651

中图分类号：

学科分类号：

摘要：

Pressure-volume analysis has provided critical insight into ventricular mechanics, and it has elucidated the underlying mechanisms of heart failure (HF). Renewed interest in ventriculovascular coupling, the interaction of the left ventricle and the arterial system, has developed from recent investigations focusing on the importance of heart rate control in systolic HF, blood pressure lability in the elderly, and acute pulmonary edema in patients with HF and a normal ejection fraction. These data suggest that abnormal ventriculovascular coupling may be an additional pathophysiological mechanism underlying the development of HF with a normal ejection fraction and may provide a target for novel therapies.

引用

页码：204 / 211

页数：7

共 174 条

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