Interaction of PTH and PTHrP with Their Receptors

Takasu H., Gardella T., Luck M., Potts J. Jr., Bringhurst F., Amino-Terminal Modifications of Human Parathyroid Hormone(PTH) Selectively Alter Phospholipase C Signaling via the Type 1 PTH Receptor: Implications for Design of Signal-Specific PTH Ligands, Biochemistry, 38, pp. 13453-13460, (1999)

Jouishomme H., Whitfield J.F., Gagnon L., Maclean S., Isaacs R., Chakravarthy B., Durkin J., Neugebauer W., Willick G., Rixon R.H., Further definition of the protein kinase C activation domain of the parathyroid hormone, J Bone Miner Res, 9, pp. 943-949, (1994)

Azarani A., Goltzman D., Orlowski J., Structurally diverse N-terminal peptides of parathyroid hormone (PTH) and PTH-related peptide (PTHRP) inhibit the Na+/H+ exchanger NHE3 isoform by binding to the PTH/PTHRP receptor type I and activating distinct signaling pathways, J Biol Chem, 271, pp. 14931-14936, (1996)

Takasu H., Bringhurst F.R., Type-1 parathyroid hormone (PTH)/ PTH-related peptide (PTHrP) receptors activate phospholipase C in response to carboxyl-truncated analogs of PTH(1-34), Endocrinology, 139, pp. 4293-4299, (1998)

Friedman P.A., Gesek F.A., Morley P., Whitfield J.F., Willick G.E., Cell-specific signaling and structure-activity relations of parathyroid hormone analogs in mouse kidney cells, Endocrinology, 140, pp. 301-309, (1999)

Caulfield M.P., McKee R.L., Goldman M.E., Duong L.T., Fisher J.E., Gay C.T., DeHaven P.A., Levy J.J., Roubini E., Nutt R.F., Chorev M., Rosenblatt M., The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: The receptor binding domains of PTH and PTH-related protein are located within the 14-34 region, Endocrinology, 127, pp. 83-87, (1990)

Nussbaum S.R., Rosenblatt M., Potts J.T. Jr., Parathyroid hormone/ renal receptor interactions: Demonstration of two receptor-binding domains, J Biol Chem, 255, pp. 10183-10187, (1980)

Abou-Samra A.-B., Uneno S., Juppner H., Keutmann H., Potts J.T. Jr., Segre G.V., Nussbaum S.R., Non-homologous sequences of parathyroid hormone and the parathyroid hormone related peptide bind to a common receptor on ROS 17/2.8 cells, Endocrinology, 125, pp. 2215-2217, (1989)

Juppner H., Schipani E., Bringhurst F.R., McClure I., Keutmann H.T., Potts J.T. Jr., Kronenberg H.M., Abou-Samra A.B., Segre G.V., Gardella T.J., The extracellular, amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor determines the binding affinity for carboxyl-terminal fragments of PTH(1-34), Endocrinology, 134, pp. 879-884, (1994)

Goltzman D., Peytremann A., Callahan E., Tregear G.W., Potts J.T. Jr., Analysis of the Requirements for Parathyroid Hormone Action in Renal Membranes with the Use of Inhibiting Analogues, J Biol Chem, 250, pp. 3199-3203, (1975)

Takasu H., Gardella T., Luck M., Potts J. Jr., Bringhurst F., Amino-Terminal Modifications of Human Parathyroid Hormone(PTH) Selectively Alter Phospholipase C Signaling via the Type 1 PTH Receptor: Implications for Design of Signal-Specific PTH Ligands, Biochemistry, 38, pp. 13453-13460, (1999)

Jouishomme H., Whitfield J.F., Gagnon L., Maclean S., Isaacs R., Chakravarthy B., Durkin J., Neugebauer W., Willick G., Rixon R.H., Further definition of the protein kinase C activation domain of the parathyroid hormone, J Bone Miner Res, 9, pp. 943-949, (1994)

Azarani A., Goltzman D., Orlowski J., Structurally diverse N-terminal peptides of parathyroid hormone (PTH) and PTH-related peptide (PTHRP) inhibit the Na+/H+ exchanger NHE3 isoform by binding to the PTH/PTHRP receptor type I and activating distinct signaling pathways, J Biol Chem, 271, pp. 14931-14936, (1996)

Takasu H., Bringhurst F.R., Type-1 parathyroid hormone (PTH)/ PTH-related peptide (PTHrP) receptors activate phospholipase C in response to carboxyl-truncated analogs of PTH(1-34), Endocrinology, 139, pp. 4293-4299, (1998)

Friedman P.A., Gesek F.A., Morley P., Whitfield J.F., Willick G.E., Cell-specific signaling and structure-activity relations of parathyroid hormone analogs in mouse kidney cells, Endocrinology, 140, pp. 301-309, (1999)

Caulfield M.P., McKee R.L., Goldman M.E., Duong L.T., Fisher J.E., Gay C.T., DeHaven P.A., Levy J.J., Roubini E., Nutt R.F., Chorev M., Rosenblatt M., The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: The receptor binding domains of PTH and PTH-related protein are located within the 14-34 region, Endocrinology, 127, pp. 83-87, (1990)

Nussbaum S.R., Rosenblatt M., Potts J.T. Jr., Parathyroid hormone/ renal receptor interactions: Demonstration of two receptor-binding domains, J Biol Chem, 255, pp. 10183-10187, (1980)

Abou-Samra A.-B., Uneno S., Juppner H., Keutmann H., Potts J.T. Jr., Segre G.V., Nussbaum S.R., Non-homologous sequences of parathyroid hormone and the parathyroid hormone related peptide bind to a common receptor on ROS 17/2.8 cells, Endocrinology, 125, pp. 2215-2217, (1989)

Juppner H., Schipani E., Bringhurst F.R., McClure I., Keutmann H.T., Potts J.T. Jr., Kronenberg H.M., Abou-Samra A.B., Segre G.V., Gardella T.J., The extracellular, amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor determines the binding affinity for carboxyl-terminal fragments of PTH(1-34), Endocrinology, 134, pp. 879-884, (1994)

Goltzman D., Peytremann A., Callahan E., Tregear G.W., Potts J.T. Jr., Analysis of the Requirements for Parathyroid Hormone Action in Renal Membranes with the Use of Inhibiting Analogues, J Biol Chem, 250, pp. 3199-3203, (1975)