Disease mechanisms in psoriasis and psoriatic arthritis.

被引:5
作者
Costello P. [1 ]
FitzGerald O. [1 ]
机构
[1] Department of Rheumatology, St. Vincent's University Hospital, Elm Park
关键词
Psoriasis; Human Leukocyte Antigen; Dermatol; Psoriatic Arthritis; Natural Killer Receptor;
D O I
10.1007/s11926-996-0013-7
中图分类号
学科分类号
摘要
Any hypothesis that tries to explain disease mechanisms in psoriasis and psoriatic arthritis (PsA) must take into account the containment of the inflammatory process to three specific sites: the skin, synovium, and enthesis. This article reviews the recent literature that advances our understanding of disease mechanisms at these specific sites. Additional progress will be achieved by research that focuses on common pathogenic pathways at these sites, in particular when searching for foreign candidates or auto-antigens triggering the T-cell-mediated immune response.
引用
收藏
页码:419 / 427
页数:8
相关论文
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