Vascular development in endometriosis

被引:166
作者
Groothuis P.G. [1 ,3 ]
Nap A.W. [1 ]
Winterhager E. [2 ]
Grümmer R. [2 ]
机构
[1] Research Institute GROW, Department of Obstetrics and Gynaecology, University Hospital Maastricht, Maastricht
[2] Institute of Anatomy, University Hospital Duisburg-Essen, Essen
[3] Research Institute GROW, Department of Obstetrics and Gynecology, Academisch Ziekenhuis Maastricht, 6229 HX Maastricht
关键词
Angiogenesis; Chronic inflammation; Endometriosis; Endometrium; Invasion; Migration; Peritoneum; Vasculogenesis;
D O I
10.1007/s10456-005-9005-x
中图分类号
学科分类号
摘要
Endometriosis, defined as the presence of endometrial tissue outside the uterus, is an estrogen-dependent disease which causes pelvic pain and subfertility in women of reproductive age. The condition has a dramatic impact on the professional, social and marital life of sufferers. Direct and indirect evidence suggests that angiogenesis is required for the development and persistence of endometriosis. In this review the state-of-the-art with regard to our understanding of the role of angiogenesis in the ectopic implantation and survival of menstrual endometrial tissue will be discussed. © Springer 2005.
引用
收藏
页码:147 / 156
页数:9
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