Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis

被引:97
作者
Randolph B Caldwell
Andrzej M Kierzek
Hiroshi Arakawa
Yuri Bezzubov
Jolanta Zaim
Petra Fiedler
Stefan Kutter
Artem Blagodatski
Diyana Kostovska
Marek Koter
Jiri Plachy
Piero Carninci
Yoshihide Hayashizaki
Jean-Marie Buerstedde
机构
[1] GSF,Institute of Molecular Radiobiology
[2] Polish Academy of Sciences,Laboratory of Systems Biology Institute of Biochemistry and Biophysics
[3] University of Surrey,School of Biomedical and Molecular Sciences
[4] Institute of Molecular Genetics,Academy of Sciences of the Czech Republic
[5] RIKEN Tsukuba Institute,Laboratory for Genome Exploration Research Project, Genomic Sciences Center and Genome Science Laboratory
[6] RIKEN Yokohama Institute,Genome Exploration Research Group, RIKEN Genomic Sciences Center
关键词
Start Codon; cDNA Insert; Translation Start Codon; Alternative Start Codon; Chicken Genome Sequence;
D O I
10.1186/gb-2004-6-1-r6
中图分类号
学科分类号
摘要
A large number of cDNA inserts were sequenced from a high-quality library of chicken bursal lymphocyte cDNAs. Comparisons to public gene databases indicate that the cDNA collection represents more than 2,000 new, full-length transcripts. This resource defines the structure and the coding potential of a large fraction of B-cell specific and housekeeping genes whose function can be analyzed by disruption in the chicken DT40 B-cell line.
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