The metabolic syndrome in children and adolescents

被引:201
作者
Cruz M.L. [1 ]
Goran M.I. [1 ]
机构
[1] Dept. of Prev. Medicine/Physiology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089
基金
美国国家卫生研究院;
关键词
Insulin Resistance; Metabolic Syndrome; Impaired Glucose Tolerance; Impaired Fasting Glucose; National Cholesterol Education Program;
D O I
10.1007/s11892-004-0012-x
中图分类号
学科分类号
摘要
The metabolic syndrome was recently defined by the Adult Treatment Panel III. Despite a lack of uniform definition of the syndrome in pediatrics, recent studies have shown that the syndrome develops during, childhood and is highly prevalent among overweight children and adolescents. The hypothesized central role of insulin resistance and obesity as a common underlying feature of the metabolic syndrome also appears to be already manifested in childhood. In view of the current obesity epidemic in children and adolescents, there is a vital need to provide adequate guidelines for the definition of the metabolic syndrome in pediatrics and for the development of screening and treatment strategies. This article focuses on the above issues, as well as on the impact of the syndrome on two major disease outcomes, type 2 diabetes and cardiovascular disease. Copyright © 2004 by Current Science Inc.
引用
收藏
页码:53 / 62
页数:9
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