Isolated systolic hypertension, pulse pressure, and arterial stiffness as risk factors for cardiovascular disease

被引：39

作者：

O'Rourke M.F. ^{[1
]}

机构：

[1] Medical Prof. Unit, St. Vincent's Hospital, University of New South Wales, Darlinghurst

来源：

Current Hypertension Reports | 1999年 / 1卷 / 3期

关键词：

Pulse Pressure; Pulse Wave Velocity; Systolic Pressure; Brachial Artery; Diastolic Pressure;

D O I：

10.1007/s11906-999-0022-9

中图分类号：

学科分类号：

摘要：

Arterial stiffening with age is responsible for isolated systolic hypertension, for elevation of systolic pressure with age, and for the majority of cardiovascular events in the elderly, especially left ventricular failure. Change in brachial pulse pressure with age underestimates change in aortic pulse pressure; change with vasodilator agents, especially nitrates, underestimates beneficial effects of these agents on the heart. New methods based on pulse wave analysis complement sphygmomanometry in assessing ill effects of aging and benefits of drug therapy for hypertension. Copyright © 1999 by Current Science Inc.

引用

页码：204 / 211

页数：7

共 38 条

[11]

Staessen J.A., Fagaro R., Thijs L., Et al., Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators, Lancet, 350, pp. 757-764, (1997)

[12]

Hansson L., Zanchetti A., Carruthers S.G., Et al., Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimal Treatment (HOT) Randomised Trial, Lancet, 351, pp. 1755-1762, (1998)

[13]

Madhavan S., Ooi W.L., Cohen H., Alderman M.H., Relation of pulses pressure and blood pressure reduction to the incidence of myocardial infarction, Hypertension, 23, pp. 395-401, (1994)

[14]

Franklin S.S., Sutton-Tyrell K., Belle S.H., Et al., The importance of pulsatile components of hypertension in predicting carotid stenosis in older adults, J Hypertens, 15, pp. 1143-1150, (1997)

[15]

Benetos A., Safar M., Rudnichi A., Et al., Pulse pressure: A predictor of long-term cardiovascular mortality in a French male population, Hypertension, 30, pp. 1410-1415, (1997)

[16]

Benetos A., Rudnichi A., Safar M., Guize L., Pulse pressure and cardiovascular mortality in normotensive and hypertensive subjects, Hypertension, 32, pp. 560-564, (1998)

[17]

Mitchell G.F., Moye L.A., Braunwald E., Et al., Sphygmomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function, Circulation, 96, pp. 4254-4260, (1997)

[18]

Franklin S.S., Khan S.A., Wong N.D., Et al., The importance of pulse pressure and systolic blood pressure in predicting coronary heart disease in older adults: The Framingham Heart Study, Circulation, (1999)

[19]

Ohtsuka S., Kakihana M., Watanabe H., Sugishita Y., Chronically decreased aortic distensibility causes deterioration of coronary perfusion during increased left ventricular contraction, J Am Coll Cardiol, 24, pp. 1406-1414, (1994)

[20]

Watanabe H., Ohtsuka S., Kakihana M., Et al., Decreased aortic compliance aggravates subendocardial ischaemia in dogs with stenosed coronary artery, Cardiovasc Res, 26, pp. 1212-1218, (1992)

← 1 2 3 4 →