Oxidative stress: Changes in pregnancy and with gestational diabetes mellitus

被引：102

作者：

Chen X. ^{[1
]}

Scholl T.O. ^{[1
]}

机构：

[1] University of Medicine Science Center, Dentistry of New Jersey-SOM, Stratford, NJ 08084, Two Medical Center Drive

来源：

Current Diabetes Reports | 2005年 / 5卷 / 4期

关键词：

Oxidative Stress; Gestational Diabetes Mellitus; Total Antioxidant Capacity; Antioxidant Status; Protein Carbonyl;

D O I：

10.1007/s11892-005-0024-1

中图分类号：

学科分类号：

摘要：

Pregnancy is susceptible to oxidative stress and antioxidant defenses can be altered in response to elevated levels of oxidative stress. Limited data in gestational diabetes mellitus (GDM) suggest that products of lipid peroxidation may be increased and antioxidant enzyme activities decreased, although the results have been inconsistent. As in type 2 diabetes mellitus (T2DM), glycemic levels in patients with GDM correlate with concentrations of lipid peroxides. The effects of supplementation with antioxidants or antioxidant-rich food in T2DM are controversial. Whether or not increased antioxidant intake can reduce the complications of GDM in both mother and fetus has not been explored. Copyright © 2005 by Current Science Inc.

引用

页码：282 / 288

页数：6

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