Protection from vascular risk in diabetic hypertension

被引：18

作者：

Corry D.B. ^{[1
]}

Tuck M.L. ^{[2
]}

机构：

[1] Division of Nephrology, Olive View UCLA Medical Center, Sylmar, CA 91342

[2] Division of Endocrinology, Veterans Affairs Greater Los Angeles Clinics, Sepulveda

来源：

Current Hypertension Reports | 2000年 / 2卷 / 2期

关键词：

Diabetic Nephropathy; Diabetic Retinopathy; Lisinopril; Renin Angiotensin System; Human Mesangial Cell;

D O I：

10.1007/s11906-000-0075-2

中图分类号：

学科分类号：

摘要：

Diabetes mellitus is a metabolic disorder characterized by hyperglycemia and associated with a high incidence of complications affecting both the microvascular and the macrovascular systems. Macrovascular disease affects the coronary arteries, the cerebral vessels, and the large peripheral arteries of the lower extremities. Microangiopathy affects the kidneys, eyes, and nerves. Both forms of complication are major causes of death and disability in diabetes. The precise pathophysiology of these vascular complications is becoming better understood, but specific treatment and prevention remain complex. Copyright © 2000 by Current Science Inc.

引用

页码：154 / 159

页数：5

共 41 条

[1]

The effect of intensive treatment of diabetes on the development and progression of long term complications in insulin dependent diabetes mellitus, N Engl J Med, 329, pp. 977-986, (1993)

[2]

Abouna G.M., Al-Adnani M.S., Kremer G.D., Et al., Reversal of diabetic nephropathy in human cadaveric kidneys after transplantation into non-diabetic recipients, Lancet, 2, SUPPL. 8362, pp. 1274-1276, (1983)

[3]

Peterson M.R., Vine A.K., Progression of retinopathy after pancreas transplantation. The University of Michigan Pancreas Transplant Evaluation Committee, Ophthalmology, 97, pp. 496-500, (1990)

[4]

Tuck M.L., Corry D.B., Pathophysiology and management of hypertension in diabetes, Annu Rev Med, 42, pp. 533-548, (1991)

[5]

Corry D.B., Tuck M.L., Hypertension and diabetes, Sem Nephrol, 5, pp. 561-570, (1991)

[6]

Henrion D., Laher I., Insulin potentiates norepinephrineinduced vascular tone by activation of protein kinase C and tyrosine kinase, Can J Physiol Pharmacol, 72, pp. 849-854, (1994)

[7]

Kelleher C., Kingston S., Barry S.M., Et al., Hypertension in diabetic clinic patients and their siblings, Diabetologia, 31, pp. 76-81, (1998)

[8]

Ferris J.B., O'Hare J.A., Kelleher C.M., Et al., Diabetic control and the renin-angiotensin system, catecholamines and blood pressure, Hypertension, 7, SUPPL. 2, pp. 58-63, (1985)

[9]

Anderson E.A., Mark A.L., The vasodilator action of insulin. Implications for the insulin hypothesis of hypertension, Hypertension, 21, pp. 136-141, (1993)

[10]

Yamaguchi T., Omaha K., Takayanagi R., Et al., Enhanced secretion of endothelin-1 by elevated glucose levels from cultured bovine aortic endothelial cells, FEBS Lett, 267, pp. 16-18, (1990)

← 1 2 3 4 5 →